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2016年10月18日 星期二

腎臟科Nephrology random notes 01

Nephrology random notes 01


1. Blood cells
- Hgb: RBC can remove NO in blood--> RBC infusion can elevate blood pressure
- Platelet decrease: cause-->drug?, infection? DIC? hematologic disease? autoimmune?

2. UTI
Urine analysis
           - pyuria+bacteriuria + symptoms?
           - no need to treat asymptomatic UTI in women except pregnant women 
           - check renal echo if UTI in men
           - Treatment:
                   *quinolone and Baktar not first line--> 
                    drug resistance carried by plasmids, save these drugs for MDR-TB; 
                   *Ceftriaxone has IM form for those who can not stay in the hospital for IV antibiotics
                   * yeast and candida--> can be viewed as normal colonies
                   * Proteus: may be related to stones

3. Proteinuria
- A/C ratio: DM, HTN patients wound check this.
- P/C ratio: generalized protein loss

4. BUN/Cr↑ (pre-renal azotemia) causes
- Breakdown: GI bleeding (RBC), trauma
- Sepsis
- High protein diet
- Steroid use

BUN↓ : may be related to liver function ↓

5. Oliguria----->AKI?
- Pre-renal: try hydration, but beware of heart, kidney, liver function, allergy
- Post-renal: try Foley tube insertion, DDx: stone, malignancy, BPH
- Renal: drug induced? use lasix

6. Skin turgor evaluation spots
- Axillary region
- Inguinal region

7. Diet and CKD in Taiwan
- Avoid: carambole , kiwi fruit, melons, papayas, brown rice, anchovy, salty soup

8.Shortness of breath
- Hypoxia: A/a gradient abnormal, ex. pulmonary edema(CO2 more soluable than O2)
- CO2 retention with muscle fatigue, ex. asthma, COPD

9. ABG/VBG in SOB patients with CKD
- Do not count anion gap because we still cannot differentiate whether metabolic acidosis is caused by infection or renal diseases
- RTA narrowly defined: RTA with normal Cr.

10.  Dialysis
- lung edema: refractory to diuretics
- pericarditis
-K+↑, EKG change(+), fail medical treatment (Cr high-->protect heeart, may not have EKG abnormality; can double-check K+ level if doubting hemolysis) 
- Uremia
- Intoxication: Ca2+, acylovir,aminophylline ,Benzodiazepam(x), with smaller molecular and less protein binding ability
- Elective: acidosis, anemia
- Uremic encephalopathy diagnosed by rule out, DDx: CVA, stroke, sepsis (BP drop after dialysis!)
High Cr without symptoms: This is a strong person ! XD

11. Spider angioma
- Estrogen↑ --> central arteriole, peripheral capillaries--> on liver cirrhosis 

12. Else
-  Imipenem: may induce seizure
-  Cardiac echo: IVS--> septum thickness, LVPW--> left ventricle thickness, concentric hypertrophy--> HTN related

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